Atypical hemolytic uremic syndrome (aHUS)
Evaluation of iptacopan in atypical hemolytic uremic syndrome: Design and rationale of the Phase 3 open-label multicenter APPELHUS study
David Kavanagh, Larry A Greenbaum, Arvind Bagga, Chien-Wei-Chen, Rajeshri G Karki, Sajita Vasudevan, Alan Charney, Marion Dahlke, and Fadi Fakhouri
Immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN)
APPARENT: A multicenter, randomized, double-blind, placebo-controlled Phase 3 study to assess the efficacy and safety of iptacopan in idiopathic (primary) immune complex-mediated membranoproliferative glomerulonephritis
David Kavanagh, Uday Kiran Veldandi, Marina Vivarelli, Andrew Bomback, Yaqin Wang, Nicholas J A Webb, Matthias Meier, Richard J H Smith